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Therapy: Stem Cell Therapy
Vaccination: Varicella-Zoster Virus Vaccine
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Total 69 results found since Jan 2013.
Public health impact of recombinant zoster vaccine for prevention of herpes zoster in US adults immunocompromised due to cancer
This study evaluates the public health impact of recombinant zoster vaccine (RZV) relative to no HZ vaccination for the prevention of HZ among adults aged ≥18 years diagnosed with selected cancers in the United States (US). A static Markov model was used to simulate three cohorts of individuals who are IC with cancer (time horizon of 30 years; one-year cycle length): hematopoietic stem cell transplant (HSCT) recipients, patients with breast cancer (BC; a solid tumor example), and patients with Hodgkin's lymphoma (HL; a hematological malignancy example). Cohort sizes reflect the estimated annual incidence of each conditio...
Source: Herpes - March 7, 2023 Category: Infectious Diseases Authors: Desmond Curran Brandon J Patterson Justin Carrico Ahmed Salem Elizabeth M La St éphane Lorenc Katherine A Hicks Sara Poston Christopher F Carpenter Source Type: research
Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed.
The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Natural History of Herpes Zoster in the Placebo Groups of Three Randomized Phase III Clinical Trials
CONCLUSION: The incidence and burden of HZ is high in immunocompetent adults aged ≥ 50 YOA and even more so in HSCT recipients aged ≥ 18 YOA.PMID:36322332 | DOI:10.1007/s40121-022-00689-7
Source: Herpes - November 2, 2022 Category: Infectious Diseases Authors: Desmond Curran Sean Matthews C éline Boutry Nicolas Lecrenier Anthony L Cunningham Kenneth Schmader Source Type: research
Adjuvanted recombinant zoster vaccine in solid organ transplant and hematopoietic stem-cell transplant recipients
Curr Opin Infect Dis. 2022 Aug 1;35(4):312-320. doi: 10.1097/QCO.0000000000000845. Epub 2022 Jul 5.ABSTRACTPURPOSE OF REVIEW: Hematopoietic stem-cell (HSCT) and solid organ transplant (SOT) recipients are particularly at risk to develop herpes zoster and its complications. A recently approved nonlive, adjuvanted recombinant zoster vaccine (aRZV) is a potential candidate to provide durable prevention of herpes zoster. This review summarizes current scientific evidence and expert recommendations for its use in these populations and offers practical clinical guidance.RECENT FINDINGS: Recent clinical trials have shown aRZV to ...
Source: Herpes - July 18, 2022 Category: Infectious Diseases Authors: Jean-Xavier Provost-Olewczynska Christiane Sigrid Eberhardt Source Type: research
Analysis of Immunity against Measles, Mumps, Rubella, and Varicella Zoster in Adult Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: A Single-Center Experience
Acta Med Okayama. 2022 Jun;76(3):247-253. doi: 10.18926/AMO/63718.ABSTRACTVaccine-preventable disease (VPD) infections are more severe in immunocompromised hosts. Vaccination against measles, mumps, rubella, and varicella zoster (VZV) (MMRV) is therefore recommended for hematopoietic stem cell transplantation (HCT) recipients. However, studies on adult HCT recipients with VPD infections are limited. At our institution, we have systematically conducted serological MMRV tests as a part of check-up examinations during long-term follow-up (LTFU) after HCT since 2015. This retrospective study aimed to evaluate changes in the se...
Source: Acta Med Okayama - July 5, 2022 Category: Universities & Medical Training Authors: Shohei Yoshida Nobuharu Fujii Chihiro Kamoi Wataru Kitamura Hideaki Fujiwara Noboru Asada Hisakazu Nishimori Keiko Fujii Ken-Ichi Matsuoka Yoshinobu Maeda Source Type: research
